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Artículo
Combination of squamous cell carcinoma antigen immunocomplex and alpha-fetoprotein in mid- and long-term prediction of hepatocellular carcinoma among cirrhotic patients
Gil Gómez, Antonio; Rojas, Ángela; Gallego Durán, Rocío; Ampuero Herrojo, Javier; Romero Gómez, Manuel; Pontisso, Patrizia; Liu, Changhai (BAISHIDENG PUBLISHING GROUP INC, 2021)BACKGROUND The combination of alpha-fetoprotein (AFP) and squamous cell carcinoma antigen immunocomplex (SCCA-IgM) have ...
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Effect of Quercetin on Hepatitis C Virus Life Cycle: From Viral to Host Targets
Rojas, Ángela; Campo, José Antonio del; Clement, Sophie; Lemasson, Mathieu; García Valdecasas, Marta; Romero Gómez, Manuel (PMC, 2016-08-22)Quercetin is a natural flavonoid, which has been shown to have anti hepatitis C virus (HCV) properties. However, the exact ...
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Emerging pharmacological treatment options for MAFLD
Rojas, Ángela; Lara-Romero, Carmen; Muñoz Hernández, Rocío; Gato, Sheila; Ampuero Herrojo, Javier; Romero Gómez, Manuel (2022)Metabolic dysfunction–associated fatty liver disease (MAFLD) prevalence and incidence is rising globally. It is associated ...
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Hepatitis C virus clearance by direct-acting antivirals agents improves endothelial dysfunction and subclinical atherosclerosis: HEPCAR study
Muñoz Hernández, Rocío; Ampuero Herrojo, Javier; Millán, Raquel; Gil-Gómez, Antonio; Rojas, Ángela; Macher, Hada C.; Stiefel García-Junco, Pablo Enrique; Romero Gómez, Manuel (Wolters Kluwer, 2020)INTRODUCTION: Hepatitis C virus (HCV) infection has been related to increased cardiovascular (CV) risk. The aim of this ...
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Impact of a Loss-of-Function Variant in HSD17B13 on Hepatic Decompensation and Mortality in Cirrhotic Patients
Gil Gómez, Antonio; Rojas, Ángela; García Lozano, María R.; Muñoz Hernández, Rocío; Gallego-Durán, Rocío; Maya Miles, Douglas; Ampuero Herrojo, Javier; Romero Gómez, Manuel (MDPI AG, 2022)Abstract: A common splice variant in HSD17B13 (rs72613567:TA) was recently found to be associated with a reduced risk of ...
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Metformin inhibits glutaminase activity and protects against hepatic encephalopathy
Bautista Palomas, Juan Dionisio; Campo Castillo, José Antonio del; Romero Gómez, Manuel; Ranchal Illescas, Isidora; Camacho Benítez, Inés; Nuñez Hospital, David; Díaz Herrero, María del Mar; Rojas, Ángela; Maraver Zamora, Marta; Ampuero Herrojo, Javier; Figueruela, Blanca (2012)Aim: To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective ...
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miRNAs in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis
Liu, Chang Hai; Ampuero Herrojo, Javier; Gil Gómez, Antonio; Montero-Vallejo, Rocío; Rojas, Ángela; Muñoz Hernández, Rocío; Gallego-Durán, Rocío; Romero Gómez, Manuel (Elsevier, 2018)Background & Aims microRNAs (miRNAs) are deregulated in non-alcoholic fatty liver disease (NAFLD) and have been proposed ...
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Natural Extracts Abolished Lipid Accumulation in Cells Harbouring non-favourable PNPLA3 genotype
Rojas, Ángela; Gallego, Paloma; Gil Gómez, Antonio; Muñoz Hernández, Rocío; Martín, Lourdes; Gallego Durán, Rocío; García Valdecasas, Marta; Campo, José A. del; Bautista Palomas, Juan Dionisio; Romero Gómez, Manuel (Elsevier, 2018)Background & aims. G-allele of PNPLA3 (rs738409) favours triglycerides accumulation and steatosis. In this study, we ...
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Systematic review and meta-analysis: analysis of variables influencing the interpretation of clinical trial results in NAFLD
Ampuero Herrojo, Javier; Gallego Durán, Rocío; Maya Miles, Douglas; Montero, Rocío; Gato, Sheila; Rojas, Ángela; Gil, Antonio; Muñoz, Rocío; Romero Gómez, Manuel (SPRINGER, 2022)Background NAFLD clinical trials have shown suboptimal results, particularly for liver fibrosis, despite the robust ...